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Peptide record

TPDB49398

Antifungal standard
45 amino acids
Basic Information
3D PDB MODEL
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TPDB49398
Antifungal
Anti-infective peptides
Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 45-aa standard natural antifungal peptide sequence curated from Antifungipept, CAFPdb, DRAMP, and other sources, with an available 3D structural model.
Sequence
INNWVRVPPCDQVCSRSNPEKDECCRAHGHAFHAHCNGGMNCYRR
Physicochemical Analysis
C212H324N76O63S7
LT
C
5169.80
8.03
10
4
11
+2
13.50
-0.929
34.67
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
7365
142.46
15
Residue Composition
number
3
A
5
R
5
N
2
D
6
C
2
E
1
Q
3
G
4
H
1
I
0
L
1
K
1
M
1
F
3
P
2
S
0
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 3 R: 5 N: 5 D: 2 C: 6 E: 2 Q: 1 G: 3 H: 4 I: 1 L: 0 K: 1 M: 1 F: 1 P: 3 S: 2 T: 0 W: 1 Y: 1 V: 3
Chemical Descriptors
45
C212H324N76O63S7
5169.80
8.03
+2
13.50
-0.929
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Antifungal
12 µM

Target

S. cerevisiae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms. dbAMP classified under the Anti-fungal function class.
Active against FUNGI such as S. cerevisiae (IC50 12 uM) but not bacteria. The peptide is inducible since mRNA level in fact body increased after