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Peptide record

TPDB49246

Antifungal standard
143 amino acids
Basic Information
3D PDB MODEL
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TPDB49246
Antifungal
Anti-infective peptides
Antifungipept CAFPdb dbAMP Peptipedia
standard
No
A 143-aa standard-residue antifungal peptide sequence curated from Antifungipept, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
DNHLLPGERLNPGNFLKQDRYMLIMQEDCNLVLYNLNKPEWATKTANQGSRCFVTLQSDGNFVIYDEHEQEGRNEAIWASKTDGENGNYVIILQKDGNLVLYSKPIFATGTNRFGSTAVVVAKRNRKAHFGVEQNIIEVTTNL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C715H1117N203O220S4
N
16205.20
5.88
18
17
54
-2
1.95
-0.520
83.15
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
18575
1.15
44
Residue Composition
number
8
A
7
R
16
N
7
D
2
C
10
E
7
Q
11
G
3
H
8
I
13
L
8
K
2
M
6
F
4
P
5
S
9
T
2
W
5
Y
10
V
Amino Acid Distribution
A: 8 R: 7 N: 16 D: 7 C: 2 E: 10 Q: 7 G: 11 H: 3 I: 8 L: 13 K: 8 M: 2 F: 6 P: 4 S: 5 T: 9 W: 2 Y: 5 V: 10
Chemical Descriptors
143 reviewed residue count
C715H1117N203O220S4 sequence-only estimate (linear, free termini)
16205.20 sequence-only estimate (linear, free termini)
5.88 sequence-only estimate (linear, free termini)
-2 sequence-only estimate (linear, free termini)
1.95 sequence-only estimate (linear, free termini)
-0.520 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.