TPDB

3D PDB MODEL

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TPDB ID TPDB49232

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Antifungipept CAFPdb dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 148-aa standard natural antifungal peptide sequence curated from Antifungipept, CAFPdb, dbAMP, and other sources, with an available 3D structural model.

Sequence

ATFRITNNCGFTVWPAGIPVGGGFQLNSKQSSNINVPAGTSAGRIWGRTGCSFNNGRGSCATGDCAGALSCTLSGQPATLAEYTIGGSQDFYDISVIDGFNLAMDFSCSTGVALKCRDANCPDAYHHPNDVATHACNGNSNYQITFCP

FASTA

>TPDB49232|Antifungal|length=148
ATFRITNNCGFTVWPAGIPVGGGFQLNSKQSSNINVPAGTSAGRIWGRTGCSFNNGRGSCATGDCAGALSCTLSGQPATLAEYTIGGSQDFYDISVIDGFNLAMDFSCSTGVALKCRDANCPDAYHHPNDVATHACNGNSNYQITFCP

Formula C658H997N191O214S11

Absent Amino Acids

Common Amino Acids G

Mass 15359.97

PI 5.76

Basic Residues 10

Acidic Residues 9

Hydrophobic Residues 50

Net Charge -2

Boman Index 8.74

Hydrophobicity -0.126

Aliphatic Index 58.78

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 17585

Absorbance 280nm 114.49

Polar Residues 57

number

15

A

5

R

13

N

8

D

10

C

1

E

5

Q

19

G

3

H

8

I

6

L

2

K

1

M

8

F

7

P

13

S

12

T

2

W

4

Y

6

V

Amino Acid Distribution

A: 15 R: 5 N: 13 D: 8 C: 10 E: 1 Q: 5 G: 19 H: 3 I: 8 L: 6 K: 2 M: 1 F: 8 P: 7 S: 13 T: 12 W: 2 Y: 4 V: 6

Length

148

Formula

C658H997N191O214S11

Mass

15359.97

PI

5.76

Net Charge

-2

Boman Index

8.74

Hydrophobicity

-0.126

Evidence 1 Activity

Source & Reference

Database Source dbAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.