TPDB

3D PDB MODEL

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TPDB ID TPDB49219

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 73-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

QLIVPCKTSEQCKSIRCSNGSAQCVNKQCQCPSLKQIYSVTDVSCKTVSDCVASHQCPTGLSACIEGKCICLP

FASTA

>TPDB49219|Antifungal|length=73
QLIVPCKTSEQCKSIRCSNGSAQCVNKQCQCPSLKQIYSVTDVSCKTVSDCVASHQCPTGLSACIEGKCICLP

Formula C319H537N93O106S12

Absent Amino Acids MFW

Common Amino Acids C

Mass 7756.05

PI 7.85

Basic Residues 8

Acidic Residues 4

Hydrophobic Residues 19

Net Charge +3

Boman Index 15.10

Hydrophobicity 0.027

Aliphatic Index 76.03

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 2240

Absorbance 280nm 28.88

Polar Residues 36

number

3

A

1

R

2

N

2

D

12

C

2

E

7

Q

3

G

1

H

5

I

4

L

6

K

0

M

0

F

4

P

10

S

4

T

0

W

1

Y

6

V

Amino Acid Distribution

A: 3 R: 1 N: 2 D: 2 C: 12 E: 2 Q: 7 G: 3 H: 1 I: 5 L: 4 K: 6 M: 0 F: 0 P: 4 S: 10 T: 4 W: 0 Y: 1 V: 6

Length

73

Formula

C319H537N93O106S12

Mass

7756.05

PI

7.85

Net Charge

+3

Boman Index

15.10

Hydrophobicity

0.027

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.