TPDB

3D PDB MODEL

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TPDB ID TPDB49213

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 75-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

ILIKESSEEERIYPFNPVASPFDPRSLNQILKIGKIGYCFDCARACMRRDRYIRTCSFERKLCRCSYSHIHHTHG

FASTA

>TPDB49213|Antifungal|length=75
ILIKESSEEERIYPFNPVASPFDPRSLNQILKIGKIGYCFDCARACMRRDRYIRTCSFERKLCRCSYSHIHHTHG

Formula C388H609N117O108S7

Absent Amino Acids W

Common Amino Acids R

Mass 8865.24

PI 8.84

Basic Residues 17

Acidic Residues 8

Hydrophobic Residues 25

Net Charge +5

Boman Index 18.21

Hydrophobicity -0.511

Aliphatic Index 70.27

Half Life

Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 6335

Absorbance 280nm 71.46

Polar Residues 22

number

3

A

9

R

2

N

3

D

6

C

5

E

1

Q

3

G

4

H

8

I

4

L

4

K

1

M

4

F

4

P

7

S

2

T

0

W

4

Y

1

V

Amino Acid Distribution

A: 3 R: 9 N: 2 D: 3 C: 6 E: 5 Q: 1 G: 3 H: 4 I: 8 L: 4 K: 4 M: 1 F: 4 P: 4 S: 7 T: 2 W: 0 Y: 4 V: 1

Length

75

Formula

C388H609N117O108S7

Mass

8865.24

PI

8.84

Net Charge

+5

Boman Index

18.21

Hydrophobicity

-0.511

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.