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Peptide record

TPDB49203

Antifungal standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB49203
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 15-aa standard natural antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
FFALQCAAKTRTRRV
Physicochemical Analysis
C78H130N26O19S1
NDEGHIMPSWY
AR
1768.11
12.12
4
0
7
+4
0.78
-0.053
65.33
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
3
A
3
R
0
N
0
D
1
C
0
E
1
Q
0
G
0
H
0
I
1
L
1
K
0
M
2
F
0
P
0
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 3 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 2 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
15
C78H130N26O19S1
1768.11
12.12
+4
0.78
-0.053
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antifungal
0.78 µM

Target

B. subtilis

Source & Reference

NA

Other

active against Gram+ B. subtilis (MIC 0.78 uM), S. aureus MRSA (MIC 6.25 uM), Gram- S. enterica (MIC 0.78 uM), P. aeruginosa (MIC 12.5 u
Evidence 2 Activity

Activity

MIC
Antifungal
6.25 µM

Target

Staphylococcus aureus MRSA

Source & Reference

NA

Other

active against Gram+ B. subtilis (MIC 0.78 uM), S. aureus MRSA (MIC 6.25 uM), Gram- S. enterica (MIC 0.78 uM), P. aeruginosa (MIC 12.5 uM), V-parahaemolyticus (MIC>50
Evidence 3 Activity

Activity

MIC
Antifungal
0.78 µM

Target

S. enterica

Source & Reference

NA

Other

active against Gram+ B. subtilis (MIC 0.78 uM), S. aureus MRSA (MIC 6.25 uM), Gram- S. enterica (MIC 0.78 uM), P. aeruginosa (MIC 12.5 uM), V-parahaemolyticus (MIC>50 uM), and fungi C. albicans (MIC
Evidence 4 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

B. subtilis (MIC 0.78 uM), S. aureus MRSA (MIC 6.25 uM), Gram- S. enterica (MIC 0.78 uM), P. aeruginosa (MIC 12.5 uM), V-parahaemolyticus (MIC>50 uM), and fungi C. albicans (MIC 12.5 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Candida albicans

Source & Reference

NA

Other

ica (MIC 0.78 uM), P. aeruginosa (MIC 12.5 uM), V-parahaemolyticus (MIC>50 uM), and fungi C. albicans (MIC 12.5 uM).