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Peptide record

TPDB49202

Antifungal standard
63 amino acids
Basic Information
3D PDB MODEL
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TPDB49202
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 63-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
SYNIGQTRLVVIQEQEPHCIGPCEIAFGNRPCNEECTSQQYAYGFCDYQTKGEDNPQCCCYTS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C301H449N83O103S8
MW
C
7134.85
4.16
4
8
16
-5
2.03
-0.687
43.33
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
7950
1.11
31
Residue Composition
number
2
A
2
R
4
N
2
D
8
C
6
E
7
Q
5
G
1
H
4
I
1
L
1
K
0
M
2
F
4
P
3
S
4
T
0
W
5
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 4 D: 2 C: 8 E: 6 Q: 7 G: 5 H: 1 I: 4 L: 1 K: 1 M: 0 F: 2 P: 4 S: 3 T: 4 W: 0 Y: 5 V: 2
Chemical Descriptors
63 reviewed residue count
C301H449N83O103S8 sequence-only estimate (linear, free termini)
7134.85 sequence-only estimate (linear, free termini)
4.16 sequence-only estimate (linear, free termini)
-5 sequence-only estimate (linear, free termini)
2.03 sequence-only estimate (linear, free termini)
-0.687 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.