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Peptide record

TPDB49196

Antifungal standard
85 amino acids
Basic Information
3D PDB MODEL
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TPDB49196
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 85-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
HEEPKVAPTEELMFAPSNQPRYCRSRQVFDGSCTDRGTPRTTCFLDFLGARSASEMPKNCDCTPQPNNKRLCECSVICTDCCVKN
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C396H630N120O130S12
W
C
9536.80
6.66
12
11
20
-0
2.63
-0.684
41.29
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
2115
0.22
32
Residue Composition
number
4
A
7
R
5
N
5
D
10
C
6
E
3
Q
3
G
1
H
1
I
4
L
4
K
2
M
4
F
8
P
6
S
7
T
0
W
1
Y
4
V
Amino Acid Distribution
A: 4 R: 7 N: 5 D: 5 C: 10 E: 6 Q: 3 G: 3 H: 1 I: 1 L: 4 K: 4 M: 2 F: 4 P: 8 S: 6 T: 7 W: 0 Y: 1 V: 4
Chemical Descriptors
85 reviewed residue count
C396H630N120O130S12 sequence-only estimate (linear, free termini)
9536.80 sequence-only estimate (linear, free termini)
6.66 sequence-only estimate (linear, free termini)
-0 sequence-only estimate (linear, free termini)
2.63 sequence-only estimate (linear, free termini)
-0.684 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.