TPDB

3D PDB MODEL

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TPDB ID TPDB49194

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 65-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

QRLVPLCKTIGYENPGKCPADGNKFCRRKLDDRYVKYKRCDCQDTKGRKQNHHRCICYMKLPCNQ

FASTA

>TPDB49194|Antifungal|length=65
QRLVPLCKTIGYENPGKCPADGNKFCRRKLDDRYVKYKRCDCQDTKGRKQNHHRCICYMKLPCNQ

Formula C328H533N107O92S9

Absent Amino Acids SW

Common Amino Acids K

Mass 7736.04

PI 9.59

Basic Residues 18

Acidic Residues 6

Hydrophobic Residues 15

Net Charge +10

Boman Index 20.86

Hydrophobicity -1.192

Aliphatic Index 46.46

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 6460

Absorbance 280nm 83.51

Polar Residues 22

number

1

A

7

R

4

N

5

D

8

C

1

E

4

Q

4

G

2

H

2

I

4

L

9

K

1

M

1

F

4

P

0

S

2

T

0

W

4

Y

2

V

Amino Acid Distribution

A: 1 R: 7 N: 4 D: 5 C: 8 E: 1 Q: 4 G: 4 H: 2 I: 2 L: 4 K: 9 M: 1 F: 1 P: 4 S: 0 T: 2 W: 0 Y: 4 V: 2

Length

65

Formula

C328H533N107O92S9

Mass

7736.04

PI

9.59

Net Charge

+10

Boman Index

20.86

Hydrophobicity

-1.192

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.