Peptide record

TPDB49193

Antifungal standard
60 amino acids
Basic Information
3D PDB MODEL
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TPDB49193
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 60-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
QRRKCDEKIVLQFCNGRNRCYEYCDTKECVAACKKKRNGEGICNGDVFSVSAQCLCLYKC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C287H467N89O88S10
HMPW
C
6893.01
8.31
12
7
17
+5
2.52
-0.557
56.83
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
5095
0.74
23
Residue Composition
number
3
A
5
R
4
N
3
D
10
C
4
E
3
Q
4
G
0
H
2
I
3
L
7
K
0
M
2
F
0
P
2
S
1
T
0
W
3
Y
4
V
Amino Acid Distribution
A: 3 R: 5 N: 4 D: 3 C: 10 E: 4 Q: 3 G: 4 H: 0 I: 2 L: 3 K: 7 M: 0 F: 2 P: 0 S: 2 T: 1 W: 0 Y: 3 V: 4
Chemical Descriptors
60 reviewed residue count
C287H467N89O88S10 sequence-only estimate (linear, free termini)
6893.01 sequence-only estimate (linear, free termini)
8.31 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
2.52 sequence-only estimate (linear, free termini)
-0.557 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.