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Peptide record

TPDB49191

Antifungal standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB49191
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 12-aa standard natural antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
WRFRIRWAWIRA
Physicochemical Analysis
C84H121N27O13
NDCEQGHLKMPSTYV
R
1717.06
12.88
4
0
8
+4
-4.40
-0.442
81.67
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
16500
960.95
0
Residue Composition
number
2
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
12
C84H121N27O13
1717.06
12.88
+4
-4.40
-0.442
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antifungal
6 µg/mL

Target

Pseudomonas aeruginosa PAO1

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 6 ug/ml), E. coli (MIC 1.6 ug/ml), S. typhimurium (MIC 6 ug/ml), S. aureus (MIC 12 ug/ml), S. epid
Evidence 2 Activity

Activity

MIC
Antifungal
1.6 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 6 ug/ml), E. coli (MIC 1.6 ug/ml), S. typhimurium (MIC 6 ug/ml), S. aureus (MIC 12 ug/ml), S. epidermidis (MIC 1.6 ug/ml),
Evidence 3 Activity

Activity

MIC
Antifungal
6 µg/mL

Target

S. typhimurium

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 6 ug/ml), E. coli (MIC 1.6 ug/ml), S. typhimurium (MIC 6 ug/ml), S. aureus (MIC 12 ug/ml), S. epidermidis (MIC 1.6 ug/ml), E. faecalis ATCC29212 (MIC 25
Evidence 4 Activity

Activity

MIC
Antifungal
12 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

P. aeruginosa PAO1 (MIC 6 ug/ml), E. coli (MIC 1.6 ug/ml), S. typhimurium (MIC 6 ug/ml), S. aureus (MIC 12 ug/ml), S. epidermidis (MIC 1.6 ug/ml), E. faecalis ATCC29212 (MIC 25 ug/ml), and C. albicans (M
Evidence 5 Activity

Activity

MIC
Antifungal
1.6 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

NA

Other

ug/ml), E. coli (MIC 1.6 ug/ml), S. typhimurium (MIC 6 ug/ml), S. aureus (MIC 12 ug/ml), S. epidermidis (MIC 1.6 ug/ml), E. faecalis ATCC29212 (MIC 25 ug/ml), and C. albicans (MIC 6 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

Enterococcus faecalis ATCC29212

Source & Reference

NA

Other

, S. typhimurium (MIC 6 ug/ml), S. aureus (MIC 12 ug/ml), S. epidermidis (MIC 1.6 ug/ml), E. faecalis ATCC29212 (MIC 25 ug/ml), and C. albicans (MIC 6 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
6 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

(MIC 12 ug/ml), S. epidermidis (MIC 1.6 ug/ml), E. faecalis ATCC29212 (MIC 25 ug/ml), and C. albicans (MIC 6 ug/ml).