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Peptide record

TPDB49187

Antifungal standard
55 amino acids
Basic Information
3D PDB MODEL
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TPDB49187
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 55-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
NMGCMAVLGSCGVITDCSGSCKTKFGQDASGDCDRDGGQGTCMCGYPCPHDKLHM
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C224H356N68O79S12
EW
G
5650.42
5.19
6
6
13
-2
1.34
-0.244
35.45
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
1990
0.35
19
Residue Composition
number
2
A
1
R
1
N
6
D
8
C
0
E
2
Q
10
G
2
H
1
I
2
L
3
K
4
M
1
F
2
P
4
S
3
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 6 C: 8 E: 0 Q: 2 G: 10 H: 2 I: 1 L: 2 K: 3 M: 4 F: 1 P: 2 S: 4 T: 3 W: 0 Y: 1 V: 2
Chemical Descriptors
55 reviewed residue count
C224H356N68O79S12 sequence-only estimate (linear, free termini)
5650.42 sequence-only estimate (linear, free termini)
5.19 sequence-only estimate (linear, free termini)
-2 sequence-only estimate (linear, free termini)
1.34 sequence-only estimate (linear, free termini)
-0.244 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.