TPDB

3D PDB MODEL

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TPDB ID TPDB49187

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 55-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

NMGCMAVLGSCGVITDCSGSCKTKFGQDASGDCDRDGGQGTCMCGYPCPHDKLHM

FASTA

>TPDB49187|Antifungal|length=55
NMGCMAVLGSCGVITDCSGSCKTKFGQDASGDCDRDGGQGTCMCGYPCPHDKLHM

Formula C224H356N68O79S12

Absent Amino Acids EW

Common Amino Acids G

Mass 5650.42

PI 5.19

Basic Residues 6

Acidic Residues 6

Hydrophobic Residues 13

Net Charge -2

Boman Index 10.06

Hydrophobicity -0.244

Aliphatic Index 35.45

Half Life

Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour

Extinction Coefficient Cystines 1990

Absorbance 280nm 35.22

Polar Residues 19

number

2

A

1

R

1

N

6

D

8

C

0

E

2

Q

10

G

2

H

1

I

2

L

3

K

4

M

1

F

2

P

4

S

3

T

0

W

1

Y

2

V

Amino Acid Distribution

A: 2 R: 1 N: 1 D: 6 C: 8 E: 0 Q: 2 G: 10 H: 2 I: 1 L: 2 K: 3 M: 4 F: 1 P: 2 S: 4 T: 3 W: 0 Y: 1 V: 2

Length

55

Formula

C224H356N68O79S12

Mass

5650.42

PI

5.19

Net Charge

-2

Boman Index

10.06

Hydrophobicity

-0.244

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.