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Peptide record

TPDB49186

Antifungal standard
65 amino acids
Basic Information
3D PDB MODEL
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TPDB49186
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 65-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
RKTVWPSSELDPKCCSNQPEFGICDSKEDDERCAQMCLDGCPTNKGGGCQPITEAPGAVCSCYCA
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C283H445N81O100S11
H
C
6934.79
4.24
6
10
14
-4
1.90
-0.546
39.08
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
7615
1.10
24
Residue Composition
number
4
A
2
R
2
N
5
D
10
C
5
E
3
Q
6
G
0
H
2
I
2
L
4
K
1
M
1
F
6
P
5
S
3
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 4 R: 2 N: 2 D: 5 C: 10 E: 5 Q: 3 G: 6 H: 0 I: 2 L: 2 K: 4 M: 1 F: 1 P: 6 S: 5 T: 3 W: 1 Y: 1 V: 2
Chemical Descriptors
65 reviewed residue count
C283H445N81O100S11 sequence-only estimate (linear, free termini)
6934.79 sequence-only estimate (linear, free termini)
4.24 sequence-only estimate (linear, free termini)
-4 sequence-only estimate (linear, free termini)
1.90 sequence-only estimate (linear, free termini)
-0.546 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.