TPDB

3D PDB MODEL

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TPDB ID TPDB49185

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 59-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

KEICCKELTKPVKCSSDPLCQKLCMEKEKYEDGHCFTILSKCLCMKRCNAKTLATELLA

FASTA

>TPDB49185|Antifungal|length=59
KEICCKELTKPVKCSSDPLCQKLCMEKEKYEDGHCFTILSKCLCMKRCNAKTLATELLA

Formula C285H482N76O86S11

Absent Amino Acids W

Common Amino Acids K

Mass 6702.08

PI 8.02

Basic Residues 12

Acidic Residues 8

Hydrophobic Residues 18

Net Charge +3

Boman Index 18.88

Hydrophobicity -0.232

Aliphatic Index 76.10

Half Life

Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 1990

Absorbance 280nm 29.69

Polar Residues 19

number

3

A

1

R

1

N

2

D

9

C

6

E

1

Q

1

G

1

H

2

I

8

L

10

K

2

M

1

F

2

P

3

S

4

T

0

W

1

Y

1

V

Amino Acid Distribution

A: 3 R: 1 N: 1 D: 2 C: 9 E: 6 Q: 1 G: 1 H: 1 I: 2 L: 8 K: 10 M: 2 F: 1 P: 2 S: 3 T: 4 W: 0 Y: 1 V: 1

Length

59

Formula

C285H482N76O86S11

Mass

6702.08

PI

8.02

Net Charge

+3

Boman Index

18.88

Hydrophobicity

-0.232

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.