Back to search

Peptide record

TPDB49181

Antifungal standard
41 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB49181
Antifungal
Anti-infective peptides
AFP-GFuse Peptipedia
standard
No
A 41-aa standard natural antifungal peptide sequence curated from AFP-GFuse and Peptipedia, with an available 3D structural model.
Sequence
VRVGPCDQVCSRTNPEKDECCRAHGHSGHSSCYGGRMNCYG
Physicochemical Analysis
C176H275N63O60S7
ILFW
CG
4457.93
7.66
8
4
7
+1
13.14
-0.898
23.66
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
3355
75.26
16
Residue Composition
number
1
A
4
R
2
N
2
D
6
C
2
E
1
Q
6
G
3
H
0
I
0
L
1
K
1
M
0
F
2
P
4
S
1
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 1 R: 4 N: 2 D: 2 C: 6 E: 2 Q: 1 G: 6 H: 3 I: 0 L: 0 K: 1 M: 1 F: 0 P: 2 S: 4 T: 1 W: 0 Y: 2 V: 3
Chemical Descriptors
41
C176H275N63O60S7
4457.93
7.66
+1
13.14
-0.898
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antifungal
5.4-7 µM

Target

Candida albicans ATCC 10231 and clinical strains

Source & Reference

NA

Other

active against C. albicans ATCC 10231 and clinical strains (MIC 5.4-7 uM) and T. rubrum (MIC 5.3 uM), but inactive against E.coli ATCC 8739 and S.aureus ATCC 6538.
Evidence 2 Activity

Activity

MIC
Antifungal
5.3 µM

Target

T. rubrum

Source & Reference

NA

Other

active against C. albicans ATCC 10231 and clinical strains (MIC 5.4-7 uM) and T. rubrum (MIC 5.3 uM), but inactive against E.coli ATCC 8739 and S.aureus ATCC 6538. Antibiofilm:fungi: It also