Peptide record

TPDB49179

Antifungal standard
66 amino acids
Basic Information
3D PDB MODEL
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TPDB49179
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 66-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
MKKFGCNTTHPFPGKCGNNGKSSWVSDMKKLPSAPKNRDIRCECSDRPSLARGMPGERVCRCDYDC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C306H492N98O94S10
Q
CK
7368.47
8.93
14
7
14
+6
2.82
-0.962
29.55
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7365
1.00
20
Residue Composition
number
2
A
6
R
4
N
5
D
7
C
2
E
0
Q
6
G
1
H
1
I
2
L
7
K
3
M
2
F
6
P
6
S
2
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 6 N: 4 D: 5 C: 7 E: 2 Q: 0 G: 6 H: 1 I: 1 L: 2 K: 7 M: 3 F: 2 P: 6 S: 6 T: 2 W: 1 Y: 1 V: 2
Chemical Descriptors
66 reviewed residue count
C306H492N98O94S10 sequence-only estimate (linear, free termini)
7368.47 sequence-only estimate (linear, free termini)
8.93 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
2.82 sequence-only estimate (linear, free termini)
-0.962 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.