TPDB

3D PDB MODEL

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TPDB ID TPDB49178

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 67-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

IVMKSSNSKERTYPVTPALNPLTGQHSLRQRQLIFCDECANACFRRKKPVRSCQRFICRCAIRDVGY

FASTA

>TPDB49178|Antifungal|length=67
IVMKSSNSKERTYPVTPALNPLTGQHSLRQRQLIFCDECANACFRRKKPVRSCQRFICRCAIRDVGY

Formula C333H547N107O93S7

Absent Amino Acids W

Common Amino Acids R

Mass 7762.09

PI 10.14

Basic Residues 14

Acidic Residues 4

Hydrophobic Residues 22

Net Charge +9

Boman Index 14.36

Hydrophobicity -0.466

Aliphatic Index 69.85

Half Life

Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 3355

Absorbance 280nm 43.22

Polar Residues 23

number

4

A

9

R

3

N

2

D

6

C

2

E

4

Q

2

G

1

H

4

I

4

L

4

K

1

M

3

F

4

P

5

S

3

T

0

W

2

Y

4

V

Amino Acid Distribution

A: 4 R: 9 N: 3 D: 2 C: 6 E: 2 Q: 4 G: 2 H: 1 I: 4 L: 4 K: 4 M: 1 F: 3 P: 4 S: 5 T: 3 W: 0 Y: 2 V: 4

Length

67

Formula

C333H547N107O93S7

Mass

7762.09

PI

10.14

Net Charge

+9

Boman Index

14.36

Hydrophobicity

-0.466

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.