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Peptide record

TPDB49177

Antifungal standard
60 amino acids
Basic Information
3D PDB MODEL
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TPDB49177
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 60-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
RTTTSGYGMLFDSVACEGGFEYCPRGGGNDKCTTFCRSLPNKYDFGVCDKIYACCCHINV
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C281H423N77O88S9
QW
CG
6576.45
6.69
7
6
18
-0
1.51
-0.192
43.83
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
6460
0.98
23
Residue Composition
number
2
A
3
R
3
N
4
D
8
C
2
E
0
Q
8
G
1
H
2
I
2
L
3
K
1
M
4
F
2
P
3
S
5
T
0
W
4
Y
3
V
Amino Acid Distribution
A: 2 R: 3 N: 3 D: 4 C: 8 E: 2 Q: 0 G: 8 H: 1 I: 2 L: 2 K: 3 M: 1 F: 4 P: 2 S: 3 T: 5 W: 0 Y: 4 V: 3
Chemical Descriptors
60 reviewed residue count
C281H423N77O88S9 sequence-only estimate (linear, free termini)
6576.45 sequence-only estimate (linear, free termini)
6.69 sequence-only estimate (linear, free termini)
-0 sequence-only estimate (linear, free termini)
1.51 sequence-only estimate (linear, free termini)
-0.192 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.