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Peptide record

TPDB49175

Antifungal standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB49175
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 12-aa standard natural antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
LPWKWRWWKWRR
Physicochemical Analysis
C96H130N28O13
ANDCEQGHIMFSTYV
W
1884.27
12.71
5
0
6
+5
-4.95
-1.967
32.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
27500
1459.45
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
2
K
0
M
0
F
1
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 2 M: 0 F: 0 P: 1 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
12
C96H130N28O13
1884.27
12.71
+5
-4.95
-1.967
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Pseudomonas aeruginosa PAO1

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 16 ug/ml), E. coli (MIC 8 ug/ml), S. typhimurium (MIC 16 ug/ml), S. aureus (MIC 8 ug/ml), S. epider
Evidence 2 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 16 ug/ml), E. coli (MIC 8 ug/ml), S. typhimurium (MIC 16 ug/ml), S. aureus (MIC 8 ug/ml), S. epidermidis (MIC 2 ug/ml), E.
Evidence 3 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

S. typhimurium

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 16 ug/ml), E. coli (MIC 8 ug/ml), S. typhimurium (MIC 16 ug/ml), S. aureus (MIC 8 ug/ml), S. epidermidis (MIC 2 ug/ml), E. faecalis ATCC29212 (MIC 31 ug/
Evidence 4 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

P. aeruginosa PAO1 (MIC 16 ug/ml), E. coli (MIC 8 ug/ml), S. typhimurium (MIC 16 ug/ml), S. aureus (MIC 8 ug/ml), S. epidermidis (MIC 2 ug/ml), E. faecalis ATCC29212 (MIC 31 ug/ml), and C. albicans (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

NA

Other

16 ug/ml), E. coli (MIC 8 ug/ml), S. typhimurium (MIC 16 ug/ml), S. aureus (MIC 8 ug/ml), S. epidermidis (MIC 2 ug/ml), E. faecalis ATCC29212 (MIC 31 ug/ml), and C. albicans (MIC 8 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
31 µg/mL

Target

Enterococcus faecalis ATCC29212

Source & Reference

NA

Other

l), S. typhimurium (MIC 16 ug/ml), S. aureus (MIC 8 ug/ml), S. epidermidis (MIC 2 ug/ml), E. faecalis ATCC29212 (MIC 31 ug/ml), and C. albicans (MIC 8 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

us (MIC 8 ug/ml), S. epidermidis (MIC 2 ug/ml), E. faecalis ATCC29212 (MIC 31 ug/ml), and C. albicans (MIC 8 ug/ml).