TPDB

3D PDB MODEL

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TPDB ID TPDB49172

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 55-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

VMNEDSILSSNKGDSLCCNDHPEFGICTNKSCNKWCLQGCTRGGFCKRKICHCYC

FASTA

>TPDB49172|Antifungal|length=55
VMNEDSILSSNKGDSLCCNDHPEFGICTNKSCNKWCLQGCTRGGFCKRKICHCYC

Formula C253H399N77O80S11

Absent Amino Acids A

Common Amino Acids C

Mass 6152.08

PI 7.73

Basic Residues 9

Acidic Residues 5

Hydrophobic Residues 12

Net Charge +2

Boman Index 10.11

Hydrophobicity -0.418

Aliphatic Index 47.82

Half Life

Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 7615

Absorbance 280nm 123.78

Polar Residues 24

number

0

A

2

R

5

N

3

D

10

C

2

E

1

Q

5

G

2

H

3

I

3

L

5

K

1

M

2

F

1

P

5

S

2

T

1

W

1

Y

1

V

Amino Acid Distribution

A: 0 R: 2 N: 5 D: 3 C: 10 E: 2 Q: 1 G: 5 H: 2 I: 3 L: 3 K: 5 M: 1 F: 2 P: 1 S: 5 T: 2 W: 1 Y: 1 V: 1

Length

55

Formula

C253H399N77O80S11

Mass

6152.08

PI

7.73

Net Charge

+2

Boman Index

10.11

Hydrophobicity

-0.418

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.