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Peptide record

TPDB49170

Antifungal standard
82 amino acids
Basic Information
3D PDB MODEL
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TPDB49170
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 82-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
HVCLMSFGSSYRVGVHITHEKVAACPRQNQRLYSCDSLRILYHYSCLTTRDLLYICDCSDFENIICLIRLLLNLDFVEVKLV
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C424H673N115O119S8
W
L
9542.19
7.04
12
8
37
+0
1.21
0.335
117.56
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
7825
0.82
27
Residue Composition
number
2
A
6
R
3
N
5
D
7
C
3
E
2
Q
2
G
4
H
6
I
13
L
2
K
1
M
3
F
1
P
7
S
3
T
0
W
5
Y
7
V
Amino Acid Distribution
A: 2 R: 6 N: 3 D: 5 C: 7 E: 3 Q: 2 G: 2 H: 4 I: 6 L: 13 K: 2 M: 1 F: 3 P: 1 S: 7 T: 3 W: 0 Y: 5 V: 7
Chemical Descriptors
82 reviewed residue count
C424H673N115O119S8 sequence-only estimate (linear, free termini)
9542.19 sequence-only estimate (linear, free termini)
7.04 sequence-only estimate (linear, free termini)
+0 sequence-only estimate (linear, free termini)
1.21 sequence-only estimate (linear, free termini)
0.335 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.