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Peptide record

TPDB49169

Antifungal standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB49169
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 17-aa standard natural antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
FRYKVVDLAVNFGKKII
Physicochemical Analysis
C97H156N24O22
CEQHMPSTW
KV
2010.45
10.46
4
1
10
+3
1.10
0.465
125.88
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
74.11
2
Residue Composition
number
1
A
1
R
1
N
1
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
3
K
0
M
2
F
0
P
0
S
0
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 3 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 3
Chemical Descriptors
17
C97H156N24O22
2010.45
10.46
+3
1.10
0.465
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antifungal
4-64 µM

Target

B. cereus

Source & Reference

NA

Other

inhibited Gram+ B. cereus (MIC 4-64 uM) and S-aureus(MIC > 64 uM), Gram- E. coli (MIC 4 uM), MDR P. aeruginosa (MIC 4-64 uM), and
Evidence 2 Activity

Activity

MIC
Antifungal
4 µM

Target

Escherichia coli

Source & Reference

NA

Other

inhibited Gram+ B. cereus (MIC 4-64 uM) and S-aureus(MIC > 64 uM), Gram- E. coli (MIC 4 uM), MDR P. aeruginosa (MIC 4-64 uM), and fungi C. albicans (MIC 32 uM) and filamentous fungu
Evidence 3 Activity

Activity

MIC
Antifungal
4-64 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

ed Gram+ B. cereus (MIC 4-64 uM) and S-aureus(MIC > 64 uM), Gram- E. coli (MIC 4 uM), MDR P. aeruginosa (MIC 4-64 uM), and fungi C. albicans (MIC 32 uM) and filamentous fungus F. oxysporum (MIC 8 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
32 µM

Target

Candida albicans

Source & Reference

NA

Other

aureus(MIC > 64 uM), Gram- E. coli (MIC 4 uM), MDR P. aeruginosa (MIC 4-64 uM), and fungi C. albicans (MIC 32 uM) and filamentous fungus F. oxysporum (MIC 8 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
8 µM

Target

F. oxysporum

Source & Reference

NA

Other

MDR P. aeruginosa (MIC 4-64 uM), and fungi C. albicans (MIC 32 uM) and filamentous fungus F. oxysporum (MIC 8 uM).