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Peptide record

TPDB49161

Antifungal standard
71 amino acids
Basic Information
3D PDB MODEL
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TPDB49161
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 71-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
HLSHEEPMKEPEYCRWTNAFNGTCSDRGNPQTMCFFDFLDAHTARVMPKNCACNDLPGNKRYCECSFVCNS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C346H515N101O108S11
I
C
8170.17
5.80
10
9
20
-2
2.37
-0.715
30.28
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
8980
1.10
26
Residue Composition
number
4
A
4
R
7
N
4
D
8
C
5
E
1
Q
3
G
3
H
0
I
3
L
3
K
3
M
5
F
5
P
4
S
4
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 4 R: 4 N: 7 D: 4 C: 8 E: 5 Q: 1 G: 3 H: 3 I: 0 L: 3 K: 3 M: 3 F: 5 P: 5 S: 4 T: 4 W: 1 Y: 2 V: 2
Chemical Descriptors
71 reviewed residue count
C346H515N101O108S11 sequence-only estimate (linear, free termini)
8170.17 sequence-only estimate (linear, free termini)
5.80 sequence-only estimate (linear, free termini)
-2 sequence-only estimate (linear, free termini)
2.37 sequence-only estimate (linear, free termini)
-0.715 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.