Peptide record

TPDB49159

Antifungal standard
78 amino acids
Basic Information
3D PDB MODEL
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TPDB49159
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 78-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
EVEPVPYCKVITWYDVKCGADGNKTCVDHLIKGHIYDVPVCDCSELTTSGILCTCQHRFPCKEPPPLHRISIRKQIRG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C387H614N108O111S8
M
C
8812.27
7.53
14
9
24
+1
1.53
-0.249
82.31
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
10470
1.19
22
Residue Composition
number
1
A
4
R
1
N
5
D
8
C
4
E
2
Q
5
G
4
H
7
I
4
L
6
K
0
M
1
F
7
P
3
S
5
T
1
W
3
Y
7
V
Amino Acid Distribution
A: 1 R: 4 N: 1 D: 5 C: 8 E: 4 Q: 2 G: 5 H: 4 I: 7 L: 4 K: 6 M: 0 F: 1 P: 7 S: 3 T: 5 W: 1 Y: 3 V: 7
Chemical Descriptors
78 reviewed residue count
C387H614N108O111S8 sequence-only estimate (linear, free termini)
8812.27 sequence-only estimate (linear, free termini)
7.53 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
1.53 sequence-only estimate (linear, free termini)
-0.249 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.