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Peptide record

TPDB49158

Antifungal standard
63 amino acids
Basic Information
3D PDB MODEL
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TPDB49158
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 63-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
LGTSPYCEKVLSRFAPPGNCLKKNGNALCKESCANEQFREGVCLHLPKPQSKLNCYCSVLKCP
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C299H483N85O87S8
DIMW
CL
6917.12
8.51
10
4
18
+5
1.39
-0.357
68.10
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
3480
0.50
23
Residue Composition
number
3
A
2
R
5
N
0
D
8
C
4
E
2
Q
4
G
1
H
0
I
8
L
7
K
0
M
2
F
6
P
5
S
1
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 3 R: 2 N: 5 D: 0 C: 8 E: 4 Q: 2 G: 4 H: 1 I: 0 L: 8 K: 7 M: 0 F: 2 P: 6 S: 5 T: 1 W: 0 Y: 2 V: 3
Chemical Descriptors
63 reviewed residue count
C299H483N85O87S8 sequence-only estimate (linear, free termini)
6917.12 sequence-only estimate (linear, free termini)
8.51 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
1.39 sequence-only estimate (linear, free termini)
-0.357 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.