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Peptide record

TPDB49153

Antifungal standard
50 amino acids
Basic Information
3D PDB MODEL
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TPDB49153
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 50-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
TRIMDDSSDCVFKGPCQRRSDCYERCGLKPPSRAALCQPMGLQGRVCCCL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C226H375N73O70S10
NHW
C
5555.51
8.10
8
5
13
+3
2.35
-0.354
54.60
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
1990
0.36
17
Residue Composition
number
2
A
6
R
0
N
4
D
8
C
1
E
3
Q
4
G
0
H
1
I
4
L
2
K
2
M
1
F
4
P
4
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 6 N: 0 D: 4 C: 8 E: 1 Q: 3 G: 4 H: 0 I: 1 L: 4 K: 2 M: 2 F: 1 P: 4 S: 4 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
50 reviewed residue count
C226H375N73O70S10 sequence-only estimate (linear, free termini)
5555.51 sequence-only estimate (linear, free termini)
8.10 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
2.35 sequence-only estimate (linear, free termini)
-0.354 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.