Peptide record

TPDB49151

Antifungal standard
55 amino acids
Basic Information
3D PDB MODEL
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TPDB49151
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 55-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
GPMRIAEARHCESLSHRFKGPCTRDSNCASVCETERFSGGNCHGFRRRCFCTKPC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C253H401N89O76S9
QWY
RC
6194.06
8.53
13
5
11
+5
3.09
-0.724
24.91
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
500
0.08
18
Residue Composition
number
3
A
8
R
2
N
1
D
8
C
4
E
0
Q
5
G
3
H
1
I
1
L
2
K
1
M
4
F
3
P
5
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 8 N: 2 D: 1 C: 8 E: 4 Q: 0 G: 5 H: 3 I: 1 L: 1 K: 2 M: 1 F: 4 P: 3 S: 5 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
55 reviewed residue count
C253H401N89O76S9 sequence-only estimate (linear, free termini)
6194.06 sequence-only estimate (linear, free termini)
8.53 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
3.09 sequence-only estimate (linear, free termini)
-0.724 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.