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Peptide record

TPDB49150

Antifungal standard
70 amino acids
Basic Information
3D PDB MODEL
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TPDB49150
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 70-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
REMAKEEVNCIGGHCPDGKKDCNCLPLIAPTMDIYETNESCRTDNECIKYCPKGCKIVDCNFGTCLCEYC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C324H515N89O108S14
QW
C
7834.02
4.58
9
12
18
-4
1.82
-0.407
55.71
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5220
0.67
25
Residue Composition
number
2
A
2
R
5
N
5
D
12
C
7
E
0
Q
5
G
1
H
5
I
3
L
6
K
2
M
1
F
4
P
1
S
4
T
0
W
3
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 5 D: 5 C: 12 E: 7 Q: 0 G: 5 H: 1 I: 5 L: 3 K: 6 M: 2 F: 1 P: 4 S: 1 T: 4 W: 0 Y: 3 V: 2
Chemical Descriptors
70 reviewed residue count
C324H515N89O108S14 sequence-only estimate (linear, free termini)
7834.02 sequence-only estimate (linear, free termini)
4.58 sequence-only estimate (linear, free termini)
-4 sequence-only estimate (linear, free termini)
1.82 sequence-only estimate (linear, free termini)
-0.407 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.