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Peptide record

TPDB49138

Antifungal standard
100 amino acids
Basic Information
3D PDB MODEL
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TPDB49138
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 100-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
NTCIEGIGNCQQCDVRCKARHGPAAKGACDSKFQLCTCNYPCGQGPSPPQPKKCYGGAGICSDRCGAQCCNQNCAQKYNQGSGFCDSIGNTSLCKCQYNC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C425H670N136O142S18
MW
C
10533.90
7.91
11
5
20
+4
1.80
-0.584
33.30
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
7085
0.67
49
Residue Composition
number
7
A
3
R
8
N
4
D
18
C
1
E
10
Q
13
G
1
H
4
I
2
L
7
K
0
M
2
F
6
P
6
S
3
T
0
W
4
Y
1
V
Amino Acid Distribution
A: 7 R: 3 N: 8 D: 4 C: 18 E: 1 Q: 10 G: 13 H: 1 I: 4 L: 2 K: 7 M: 0 F: 2 P: 6 S: 6 T: 3 W: 0 Y: 4 V: 1
Chemical Descriptors
100 reviewed residue count
C425H670N136O142S18 sequence-only estimate (linear, free termini)
10533.90 sequence-only estimate (linear, free termini)
7.91 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
1.80 sequence-only estimate (linear, free termini)
-0.584 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.