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Peptide record

TPDB49133

Antifungal standard
72 amino acids
Basic Information
3D PDB MODEL
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TPDB49133
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 72-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
MMQIKFLFTFLALLMMVILGAKEADADCLSGRYRGPCAVWDNETCRRVCREEGRGRVSGHCSARLQCWCEGC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C347H555N105O98S12
RC
8150.59
7.85
11
8
29
+2
1.63
0.033
73.19
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12990
1.59
17
Residue Composition
number
6
A
8
R
1
N
3
D
8
C
5
E
2
Q
7
G
1
H
2
I
7
L
2
K
4
M
3
F
1
P
3
S
2
T
2
W
1
Y
4
V
Amino Acid Distribution
A: 6 R: 8 N: 1 D: 3 C: 8 E: 5 Q: 2 G: 7 H: 1 I: 2 L: 7 K: 2 M: 4 F: 3 P: 1 S: 3 T: 2 W: 2 Y: 1 V: 4
Chemical Descriptors
72 reviewed residue count
C347H555N105O98S12 sequence-only estimate (linear, free termini)
8150.59 sequence-only estimate (linear, free termini)
7.85 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
1.63 sequence-only estimate (linear, free termini)
0.033 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.