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Peptide record

TPDB49129

Antifungal standard
58 amino acids
Basic Information
3D PDB MODEL
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TPDB49129
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 58-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
ENQKMVGEAKQCKTGWACFGEDACKEKCMAKYKGVGTVTYFPFPPETIIIYCECLYDC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C291H441N69O86S9
RHS
CK
6570.65
5.02
7
8
21
-1
0.98
-0.253
48.79
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
11835
1.80
18
Residue Composition
number
4
A
0
R
1
N
2
D
7
C
6
E
2
Q
5
G
0
H
3
I
1
L
7
K
2
M
3
F
3
P
0
S
4
T
1
W
4
Y
3
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 2 C: 7 E: 6 Q: 2 G: 5 H: 0 I: 3 L: 1 K: 7 M: 2 F: 3 P: 3 S: 0 T: 4 W: 1 Y: 4 V: 3
Chemical Descriptors
58 reviewed residue count
C291H441N69O86S9 sequence-only estimate (linear, free termini)
6570.65 sequence-only estimate (linear, free termini)
5.02 sequence-only estimate (linear, free termini)
-1 sequence-only estimate (linear, free termini)
0.98 sequence-only estimate (linear, free termini)
-0.253 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.