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Peptide record

TPDB49127

Antifungal standard
64 amino acids
Basic Information
3D PDB MODEL
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TPDB49127
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 64-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
NTGCFDYDVYQPCDHCRERCLKYYPVTRKAICRKNHCVCIGPCPNDKAIPNVKLFKNVKEQILS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C325H514N94O91S8
MW
C
7450.71
8.50
13
6
20
+5
2.08
-0.528
68.44
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
6460
0.87
22
Residue Composition
number
2
A
4
R
5
N
4
D
8
C
2
E
2
Q
2
G
2
H
4
I
3
L
7
K
0
M
2
F
5
P
1
S
2
T
0
W
4
Y
5
V
Amino Acid Distribution
A: 2 R: 4 N: 5 D: 4 C: 8 E: 2 Q: 2 G: 2 H: 2 I: 4 L: 3 K: 7 M: 0 F: 2 P: 5 S: 1 T: 2 W: 0 Y: 4 V: 5
Chemical Descriptors
64 reviewed residue count
C325H514N94O91S8 sequence-only estimate (linear, free termini)
7450.71 sequence-only estimate (linear, free termini)
8.50 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
2.08 sequence-only estimate (linear, free termini)
-0.528 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.