TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB49122

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 70-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

MVQIKFLFVFLAVMTIVVLAANMADADCLSGKYKGPCAVWDNEMCRRICKEEGHISGHCSPSLKCWCEGC

FASTA

>TPDB49122|Antifungal|length=70
MVQIKFLFVFLAVMTIVVLAANMADADCLSGKYKGPCAVWDNEMCRRICKEEGHISGHCSPSLKCWCEGC

Formula C339H534N90O94S12

Absent Amino Acids

Common Amino Acids C

Mass 7759.24

PI 6.85

Basic Residues 9

Acidic Residues 7

Hydrophobic Residues 31

Net Charge -0

Boman Index 7.78

Hydrophobicity 0.384

Aliphatic Index 83.57

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 12990

Absorbance 280nm 167.41

Polar Residues 17

number

6

A

2

R

2

N

3

D

8

C

4

E

1

Q

5

G

2

H

4

I

5

L

5

K

4

M

3

F

2

P

4

S

1

T

2

W

1

Y

6

V

Amino Acid Distribution

A: 6 R: 2 N: 2 D: 3 C: 8 E: 4 Q: 1 G: 5 H: 2 I: 4 L: 5 K: 5 M: 4 F: 3 P: 2 S: 4 T: 1 W: 2 Y: 1 V: 6

Length

70

Formula

C339H534N90O94S12

Mass

7759.24

PI

6.85

Net Charge

-0

Boman Index

7.78

Hydrophobicity

0.384

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.