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Peptide record

TPDB49114

Antifungal standard
55 amino acids
Basic Information
3D PDB MODEL
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TPDB49114
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 55-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
NMGCIQIIGRCIKIPDCSASCRKFLGPHASGYCDNDGAGGTCICTYPCQTKEIHM
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C245H392N72O76S10
WV
C
5882.84
7.51
7
4
16
+1
1.13
-0.045
62.18
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
3480
0.59
20
Residue Composition
number
3
A
2
R
2
N
3
D
8
C
1
E
2
Q
7
G
2
H
7
I
1
L
3
K
2
M
1
F
3
P
3
S
3
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 3 R: 2 N: 2 D: 3 C: 8 E: 1 Q: 2 G: 7 H: 2 I: 7 L: 1 K: 3 M: 2 F: 1 P: 3 S: 3 T: 3 W: 0 Y: 2 V: 0
Chemical Descriptors
55 reviewed residue count
C245H392N72O76S10 sequence-only estimate (linear, free termini)
5882.84 sequence-only estimate (linear, free termini)
7.51 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
1.13 sequence-only estimate (linear, free termini)
-0.045 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.