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Peptide record

TPDB49112

Antifungal standard
74 amino acids
Basic Information
3D PDB MODEL
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TPDB49112
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 74-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
QFRGIKQCEMKCYSTPECNATCLHEGYEEGKCLKSWDGGVECCCLGLLASSHQDSSPISSPHYIIFHGICILNI
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C353H545N95O109S10
C
8184.38
5.65
9
8
23
-3
1.03
-0.088
75.14
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
10470
1.28
27
Residue Composition
number
2
A
1
R
2
N
2
D
9
C
6
E
3
Q
7
G
4
H
7
I
6
L
4
K
1
M
2
F
3
P
8
S
2
T
1
W
3
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 2 C: 9 E: 6 Q: 3 G: 7 H: 4 I: 7 L: 6 K: 4 M: 1 F: 2 P: 3 S: 8 T: 2 W: 1 Y: 3 V: 1
Chemical Descriptors
74 reviewed residue count
C353H545N95O109S10 sequence-only estimate (linear, free termini)
8184.38 sequence-only estimate (linear, free termini)
5.65 sequence-only estimate (linear, free termini)
-3 sequence-only estimate (linear, free termini)
1.03 sequence-only estimate (linear, free termini)
-0.088 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.