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Peptide record

TPDB49111

Antifungal standard
79 amino acids
Basic Information
3D PDB MODEL
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TPDB49111
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 79-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
RTGYVSCKTNSDCVKLKCPTPFGGPKCISGSCECPFKELMTLPNDTNYGVAACIDYCKAKGEIVYACILNHCYSYKPPM
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C377H588N96O112S12
QW
C
8642.11
7.95
10
6
26
+3
0.96
-0.142
59.24
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
9565
1.11
30
Residue Composition
number
4
A
1
R
4
N
3
D
10
C
3
E
0
Q
6
G
1
H
4
I
4
L
8
K
2
M
2
F
7
P
5
S
5
T
0
W
6
Y
4
V
Amino Acid Distribution
A: 4 R: 1 N: 4 D: 3 C: 10 E: 3 Q: 0 G: 6 H: 1 I: 4 L: 4 K: 8 M: 2 F: 2 P: 7 S: 5 T: 5 W: 0 Y: 6 V: 4
Chemical Descriptors
79 reviewed residue count
C377H588N96O112S12 sequence-only estimate (linear, free termini)
8642.11 sequence-only estimate (linear, free termini)
7.95 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
0.96 sequence-only estimate (linear, free termini)
-0.142 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.