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Peptide record

TPDB49110

Antifungal standard
53 amino acids
Basic Information
3D PDB MODEL
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TPDB49110
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 53-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KSMVEVNAAHKWYIVEGLCSKFPDCNKHCKEQKFPGGTCLKLGVNMMCTCIYS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C261H411N69O73S9
R
K
5972.09
8.30
9
4
19
+3
0.89
-0.126
62.45
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
8855
1.48
17
Residue Composition
number
2
A
0
R
3
N
1
D
6
C
3
E
1
Q
4
G
2
H
2
I
3
L
7
K
3
M
2
F
2
P
3
S
2
T
1
W
2
Y
4
V
Amino Acid Distribution
A: 2 R: 0 N: 3 D: 1 C: 6 E: 3 Q: 1 G: 4 H: 2 I: 2 L: 3 K: 7 M: 3 F: 2 P: 2 S: 3 T: 2 W: 1 Y: 2 V: 4
Chemical Descriptors
53 reviewed residue count
C261H411N69O73S9 sequence-only estimate (linear, free termini)
5972.09 sequence-only estimate (linear, free termini)
8.30 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
0.89 sequence-only estimate (linear, free termini)
-0.126 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.