Peptide record

TPDB49104

Antifungal standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB49104
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 46-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
ANCVNYFEITFPEVCEANWCAAECLKAYKNGKGTCWQKFCQCVYDC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C233H338N58O68S8
RHMS
C
5296.07
4.79
4
5
18
-1
0.97
-0.115
46.74
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
15970
3.02
19
Residue Composition
number
5
A
0
R
4
N
1
D
8
C
4
E
2
Q
2
G
0
H
1
I
1
L
4
K
0
M
3
F
1
P
0
S
2
T
2
W
3
Y
3
V
Amino Acid Distribution
A: 5 R: 0 N: 4 D: 1 C: 8 E: 4 Q: 2 G: 2 H: 0 I: 1 L: 1 K: 4 M: 0 F: 3 P: 1 S: 0 T: 2 W: 2 Y: 3 V: 3
Chemical Descriptors
46 reviewed residue count
C233H338N58O68S8 sequence-only estimate (linear, free termini)
5296.07 sequence-only estimate (linear, free termini)
4.79 sequence-only estimate (linear, free termini)
-1 sequence-only estimate (linear, free termini)
0.97 sequence-only estimate (linear, free termini)
-0.115 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.