TPDB

3D PDB MODEL

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TPDB ID TPDB49102

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 55-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

KRHCSTIILPESPCVPQDCVEYCFEEYNGGGTCIASKTGRTTNCMCTYNCHGNNL

FASTA

>TPDB49102|Antifungal|length=55
KRHCSTIILPESPCVPQDCVEYCFEEYNGGGTCIASKTGRTTNCMCTYNCHGNNL

Formula C251H391N73O84S9

Absent Amino Acids W

Common Amino Acids C

Mass 6063.84

PI 6.03

Basic Residues 6

Acidic Residues 5

Hydrophobic Residues 13

Net Charge -1

Boman Index 11.96

Hydrophobicity -0.418

Aliphatic Index 47.82

Half Life

Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 4970

Absorbance 280nm 81.96

Polar Residues 26

number

1

A

2

R

5

N

1

D

8

C

4

E

1

Q

5

G

2

H

3

I

2

L

2

K

1

M

1

F

3

P

3

S

6

T

0

W

3

Y

2

V

Amino Acid Distribution

A: 1 R: 2 N: 5 D: 1 C: 8 E: 4 Q: 1 G: 5 H: 2 I: 3 L: 2 K: 2 M: 1 F: 1 P: 3 S: 3 T: 6 W: 0 Y: 3 V: 2

Length

55

Formula

C251H391N73O84S9

Mass

6063.84

PI

6.03

Net Charge

-1

Boman Index

11.96

Hydrophobicity

-0.418

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.