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Peptide record

TPDB49095

Antifungal standard
90 amino acids
Basic Information
3D PDB MODEL
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TPDB49095
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb dbAMP Peptipedia
standard
No
A 90-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
ITCNDVTGNLTPCLPYLRSGGKPTPACCAGAKKLLGATRTQADRRTACKCAKTAAPQLKVRPDMASSLPGKCGISTSIPINPNVNCNTIP
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C392H666N120O121S9
EHFW
APT
9284.87
9.58
12
3
27
+9
1.39
-0.198
72.78
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1990
0.21
32
Residue Composition
number
10
A
5
R
6
N
3
D
8
C
0
E
2
Q
7
G
0
H
5
I
7
L
7
K
1
M
0
F
10
P
5
S
10
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 10 R: 5 N: 6 D: 3 C: 8 E: 0 Q: 2 G: 7 H: 0 I: 5 L: 7 K: 7 M: 1 F: 0 P: 10 S: 5 T: 10 W: 0 Y: 1 V: 3
Chemical Descriptors
90 reviewed residue count
C392H666N120O121S9 sequence-only estimate (linear, free termini)
9284.87 sequence-only estimate (linear, free termini)
9.58 sequence-only estimate (linear, free termini)
+9 sequence-only estimate (linear, free termini)
1.39 sequence-only estimate (linear, free termini)
-0.198 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.