TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB49088

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 52-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

IESPIFTGNKCSDPTGMDKDGKCLDYCHAQGYPGGSCIGFIDQGYMCVCKVG

FASTA

>TPDB49088|Antifungal|length=52
IESPIFTGNKCSDPTGMDKDGKCLDYCHAQGYPGGSCIGFIDQGYMCVCKVG

Formula C235H359N61O76S8

Absent Amino Acids RW

Common Amino Acids G

Mass 5511.28

PI 4.62

Basic Residues 5

Acidic Residues 6

Hydrophobic Residues 15

Net Charge -2

Boman Index 7.97

Hydrophobicity -0.192

Aliphatic Index 50.58

Half Life

Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 4845

Absorbance 280nm 87.91

Polar Residues 17

number

1

A

0

R

1

N

5

D

6

C

1

E

2

Q

9

G

1

H

4

I

1

L

4

K

2

M

2

F

3

P

3

S

2

T

0

W

3

Y

2

V

Amino Acid Distribution

A: 1 R: 0 N: 1 D: 5 C: 6 E: 1 Q: 2 G: 9 H: 1 I: 4 L: 1 K: 4 M: 2 F: 2 P: 3 S: 3 T: 2 W: 0 Y: 3 V: 2

Length

52

Formula

C235H359N61O76S8

Mass

5511.28

PI

4.62

Net Charge

-2

Boman Index

7.97

Hydrophobicity

-0.192

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.