TPDB

3D PDB MODEL

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TPDB ID TPDB49086

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 61-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

GLDPMAANLRVRKDIFIGGCGRDGNKTCMKDFVKKGGVMNKPISCECDNLGYEHLCRCNFS

FASTA

>TPDB49086|Antifungal|length=61
GLDPMAANLRVRKDIFIGGCGRDGNKTCMKDFVKKGGVMNKPISCECDNLGYEHLCRCNFS

Formula C284H460N86O85S9

Absent Amino Acids QW

Common Amino Acids G

Mass 6727.84

PI 8.30

Basic Residues 11

Acidic Residues 7

Hydrophobic Residues 19

Net Charge +3

Boman Index 14.05

Hydrophobicity -0.370

Aliphatic Index 62.30

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1865

Absorbance 280nm 27.72

Polar Residues 15

number

2

A

4

R

5

N

5

D

6

C

2

E

0

Q

8

G

1

H

3

I

4

L

6

K

3

M

3

F

2

P

2

S

1

T

0

W

1

Y

3

V

Amino Acid Distribution

A: 2 R: 4 N: 5 D: 5 C: 6 E: 2 Q: 0 G: 8 H: 1 I: 3 L: 4 K: 6 M: 3 F: 3 P: 2 S: 2 T: 1 W: 0 Y: 1 V: 3

Length

61

Formula

C284H460N86O85S9

Mass

6727.84

PI

8.30

Net Charge

+3

Boman Index

14.05

Hydrophobicity

-0.370

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.