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Peptide record

TPDB49083

Antifungal standard
48 amino acids
Basic Information
3D PDB MODEL
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TPDB49083
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 48-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
QMNDCDCDHDHRCGEWEDESHGNCKQHHLRVVCTCTLDCLDISSTSNA
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C215H331N71O81S8
FPY
DC
5462.90
4.56
8
10
9
-7
3.07
-0.894
46.67
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
5875
1.08
19
Residue Composition
number
1
A
2
R
3
N
7
D
7
C
3
E
2
Q
2
G
5
H
1
I
3
L
1
K
1
M
0
F
0
P
4
S
3
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 3 D: 7 C: 7 E: 3 Q: 2 G: 2 H: 5 I: 1 L: 3 K: 1 M: 1 F: 0 P: 0 S: 4 T: 3 W: 1 Y: 0 V: 2
Chemical Descriptors
48 reviewed residue count
C215H331N71O81S8 sequence-only estimate (linear, free termini)
5462.90 sequence-only estimate (linear, free termini)
4.56 sequence-only estimate (linear, free termini)
-7 sequence-only estimate (linear, free termini)
3.07 sequence-only estimate (linear, free termini)
-0.894 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.