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Peptide record

TPDB49081

Antifungal standard
64 amino acids
Basic Information
3D PDB MODEL
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TPDB49081
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 64-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
QVKPTGCQGGQRYRGKCGTNGTKTCVKDMMLPKLFKTKRCDCQDMLGTFKGWHFCTCYSGRPGC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C303H484N92O86S11
AEI
G
7144.40
9.49
13
3
14
+9
1.95
-0.695
27.34
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
8980
1.26
23
Residue Composition
number
0
A
4
R
1
N
3
D
8
C
0
E
4
Q
10
G
1
H
0
I
3
L
8
K
3
M
3
F
3
P
1
S
7
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 3 C: 8 E: 0 Q: 4 G: 10 H: 1 I: 0 L: 3 K: 8 M: 3 F: 3 P: 3 S: 1 T: 7 W: 1 Y: 2 V: 2
Chemical Descriptors
64 reviewed residue count
C303H484N92O86S11 sequence-only estimate (linear, free termini)
7144.40 sequence-only estimate (linear, free termini)
9.49 sequence-only estimate (linear, free termini)
+9 sequence-only estimate (linear, free termini)
1.95 sequence-only estimate (linear, free termini)
-0.695 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.