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Peptide record

TPDB49079

Antifungal standard
57 amino acids
Basic Information
3D PDB MODEL
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TPDB49079
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 57-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
MVNGQCSFPQPVGPNGKCVPKDCKSLCHKKYKGGSICTTGKPNICMCLVCRRRSPEV
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C260H434N80O74S10
AW
C
6185.40
9.28
11
2
13
+8
1.58
-0.389
52.81
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1990
0.32
20
Residue Composition
number
0
A
3
R
3
N
1
D
8
C
1
E
2
Q
6
G
1
H
2
I
2
L
7
K
2
M
1
F
6
P
4
S
2
T
0
W
1
Y
5
V
Amino Acid Distribution
A: 0 R: 3 N: 3 D: 1 C: 8 E: 1 Q: 2 G: 6 H: 1 I: 2 L: 2 K: 7 M: 2 F: 1 P: 6 S: 4 T: 2 W: 0 Y: 1 V: 5
Chemical Descriptors
57 reviewed residue count
C260H434N80O74S10 sequence-only estimate (linear, free termini)
6185.40 sequence-only estimate (linear, free termini)
9.28 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
1.58 sequence-only estimate (linear, free termini)
-0.389 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.