TPDB

3D PDB MODEL

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TPDB ID TPDB49076

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 38-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

MLMACYSAGQLGCLVFCNEAEYSYGKCIGRGRCCCYDL

FASTA

>TPDB49076|Antifungal|length=38
MLMACYSAGQLGCLVFCNEAEYSYGKCIGRGRCCCYDL

Formula C177H273N47O53S9

Absent Amino Acids HPTW

Common Amino Acids C

Mass 4195.94

PI 6.05

Basic Residues 3

Acidic Residues 3

Hydrophobic Residues 16

Net Charge -0

Boman Index -0.83

Hydrophobicity 0.374

Aliphatic Index 66.84

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 6335

Absorbance 280nm 150.98

Polar Residues 15

number

3

A

2

R

1

N

1

D

7

C

2

E

1

Q

5

G

0

H

1

I

4

L

1

K

2

M

1

F

0

P

2

S

0

T

0

W

4

Y

1

V

Amino Acid Distribution

A: 3 R: 2 N: 1 D: 1 C: 7 E: 2 Q: 1 G: 5 H: 0 I: 1 L: 4 K: 1 M: 2 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 4 V: 1

Length

38

Formula

C177H273N47O53S9

Mass

4195.94

PI

6.05

Net Charge

-0

Boman Index

-0.83

Hydrophobicity

0.374

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.