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Peptide record

TPDB49067

Antifungal standard
50 amino acids
Basic Information
3D PDB MODEL
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TPDB49067
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 50-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
FTIAEPYIHPCMKGFCSFKSECANKCIFMGHHKGGDCIGGLDGIYCCCLA
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C237H357N61O65S10
RQWV
C
5421.41
6.94
7
4
18
-0
0.20
0.338
60.60
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
3480
0.64
14
Residue Composition
number
3
A
0
R
1
N
2
D
8
C
2
E
0
Q
7
G
3
H
5
I
2
L
4
K
2
M
4
F
2
P
2
S
1
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 2 C: 8 E: 2 Q: 0 G: 7 H: 3 I: 5 L: 2 K: 4 M: 2 F: 4 P: 2 S: 2 T: 1 W: 0 Y: 2 V: 0
Chemical Descriptors
50 reviewed residue count
C237H357N61O65S10 sequence-only estimate (linear, free termini)
5421.41 sequence-only estimate (linear, free termini)
6.94 sequence-only estimate (linear, free termini)
-0 sequence-only estimate (linear, free termini)
0.20 sequence-only estimate (linear, free termini)
0.338 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.