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Peptide record

TPDB49066

Antifungal standard
54 amino acids
Basic Information
3D PDB MODEL
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TPDB49066
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 54-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
LPSSVINGFGYDYCIVECSITFLDDACKPLCIDRGYSDGGCIGLSPHFKCCCKK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C256H394N64O77S8
QMW
C
5856.81
5.40
6
6
18
-1
0.74
0.235
77.59
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
4970
0.85
18
Residue Composition
number
1
A
1
R
1
N
5
D
8
C
1
E
0
Q
6
G
1
H
5
I
4
L
4
K
0
M
3
F
3
P
5
S
1
T
0
W
3
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 5 C: 8 E: 1 Q: 0 G: 6 H: 1 I: 5 L: 4 K: 4 M: 0 F: 3 P: 3 S: 5 T: 1 W: 0 Y: 3 V: 2
Chemical Descriptors
54 reviewed residue count
C256H394N64O77S8 sequence-only estimate (linear, free termini)
5856.81 sequence-only estimate (linear, free termini)
5.40 sequence-only estimate (linear, free termini)
-1 sequence-only estimate (linear, free termini)
0.74 sequence-only estimate (linear, free termini)
0.235 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.