TPDB

3D PDB MODEL

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TPDB ID TPDB49066

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 54-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

LPSSVINGFGYDYCIVECSITFLDDACKPLCIDRGYSDGGCIGLSPHFKCCCKK

FASTA

>TPDB49066|Antifungal|length=54
LPSSVINGFGYDYCIVECSITFLDDACKPLCIDRGYSDGGCIGLSPHFKCCCKK

Formula C256H394N64O77S8

Absent Amino Acids QMW

Common Amino Acids C

Mass 5856.81

PI 5.40

Basic Residues 6

Acidic Residues 6

Hydrophobic Residues 18

Net Charge -1

Boman Index 4.57

Hydrophobicity 0.235

Aliphatic Index 77.59

Half Life

Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 4970

Absorbance 280nm 84.86

Polar Residues 18

number

1

A

1

R

1

N

5

D

8

C

1

E

0

Q

6

G

1

H

5

I

4

L

4

K

0

M

3

F

3

P

5

S

1

T

0

W

3

Y

2

V

Amino Acid Distribution

A: 1 R: 1 N: 1 D: 5 C: 8 E: 1 Q: 0 G: 6 H: 1 I: 5 L: 4 K: 4 M: 0 F: 3 P: 3 S: 5 T: 1 W: 0 Y: 3 V: 2

Length

54

Formula

C256H394N64O77S8

Mass

5856.81

PI

5.40

Net Charge

-1

Boman Index

4.57

Hydrophobicity

0.235

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.