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Peptide record

TPDB49065

Antifungal standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB49065
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 25-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
ISCQDVKQSLAPCLPYVTGRAPKPA
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C116H192N32O34S2
NEHMFW
P
2643.11
9.03
3
1
9
+2
0.94
-0.092
82.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1615
0.61
8
Residue Composition
number
3
A
1
R
0
N
1
D
2
C
0
E
2
Q
1
G
0
H
1
I
2
L
2
K
0
M
0
F
4
P
2
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 1 C: 2 E: 0 Q: 2 G: 1 H: 0 I: 1 L: 2 K: 2 M: 0 F: 0 P: 4 S: 2 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
25 reviewed residue count
C116H192N32O34S2 sequence-only estimate (linear, free termini)
2643.11 sequence-only estimate (linear, free termini)
9.03 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
0.94 sequence-only estimate (linear, free termini)
-0.092 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.