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Peptide record

TPDB49063

Antifungal standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB49063
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 32-aa standard natural antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
AGGRLFDKIRQVIRKGAGGRLFDKIRQVIRKG
Physicochemical Analysis
C160H278N56O39
NCEHMPSTWY
RG
3610.32
12.41
10
2
12
+8
7.68
-0.494
97.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
6
R
0
N
2
D
0
C
0
E
2
Q
6
G
0
H
4
I
2
L
4
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 6 N: 0 D: 2 C: 0 E: 0 Q: 2 G: 6 H: 0 I: 4 L: 2 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
32
C160H278N56O39
3610.32
12.41
+8
7.68
-0.494
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antifungal
0.625 µM

Target

Escherichia coli

Source & Reference

NA

Other

active against E. coli (MIC 0.625 uM), P. aeruginosa (MIC 1.25 uM), S. aureus (MIC 1.25 uM), and C. albicans (MIC 2.5 uM). Warn
Evidence 2 Activity

Activity

MIC
Antifungal
1.25 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

active against E. coli (MIC 0.625 uM), P. aeruginosa (MIC 1.25 uM), S. aureus (MIC 1.25 uM), and C. albicans (MIC 2.5 uM). Warning: Nonstandard assays.
Evidence 3 Activity

Activity

MIC
Antifungal
1.25 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

active against E. coli (MIC 0.625 uM), P. aeruginosa (MIC 1.25 uM), S. aureus (MIC 1.25 uM), and C. albicans (MIC 2.5 uM). Warning: Nonstandard assays.
Evidence 4 Activity

Activity

MIC
Antifungal
2.5 µM

Target

Candida albicans

Source & Reference

NA

Other

against E. coli (MIC 0.625 uM), P. aeruginosa (MIC 1.25 uM), S. aureus (MIC 1.25 uM), and C. albicans (MIC 2.5 uM). Warning: Nonstandard assays.